Yes. You can create any number of Allotment notification templates under Team Helpdesk Manager > Templates Manager > Allotment Templates tab.
And choose the specific allotment when a case is raised but before the notification is send out in the case form.
You can also set the default allotment to use under Team Helpdesk Manager > Case Options > Default Values so the chosen allotment is set to newly created case by default.
Additionally, under Team Helpdesk Manager > Email Monitoring panel, you can specify a different auto-response for each monitored mailbox. For instance, if someone sends an e-mail to UK.Support@myCompany.com, you would want to inform the customer that their e-mail will be responded to within 2 hours between 9am and 5:30pm UK time. If they send a new case to US.Support@myCompany.com, you can inform the customer that their e-mail will be responded to within 3 hours between 9am and 5:30pm Eastern Standard Time.